Thursday, 9 August 2012

Chronic Inflammatory Diseases-Allergic Asthma-Airway Damage-Dna Circuitry-Immune Cells

Rewiring DNA circuitry could help treat asthma

Reprogramming asthma-promoting immune cells in mice diminishes airway damage and inflammation, and could potentially lead to new treatments for people with asthma, researchers have found. The researchers were able to reprogram the asthma-promoting cells (called Th2 [T-helper 2] cells) after identifying an enzyme that modifies the DNA of these cells. The enzyme could be a target for the development of new treatments for chronic inflammatory diseases, in particular allergic asthma, caused by an excess of Th2 cells. read more..

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